Publicación: Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius
dc.contributor.author | Fuente Rubio, Mercedes de la | |
dc.contributor.author | Martín Folgar, Raquel | |
dc.contributor.author | Martínez Paz, Pedro | |
dc.contributor.author | Cortés Rubio, María Estrella del Perpetuo | |
dc.contributor.author | Martínez Guitarte, José Luis | |
dc.contributor.author | Morales Camarzana, Consolación Mónica | |
dc.contributor.orcid | https://orcid.org/0000-0002-5772-8153 | |
dc.date.accessioned | 2024-10-03T17:13:07Z | |
dc.date.available | 2024-10-03T17:13:07Z | |
dc.date.issued | 2021-09-13 | |
dc.description | The registered version of this article, first published in Environmental Science and Pollution Research , is available online at the publisher's website: Springer, https://doi.org/10.1007/s11356-021-16339-3 | |
dc.description | La versión registrada de este artículo, publicado por primera vez en Environmental Science and Pollution Research , está disponible en línea en el sitio web del editor: Springer, https://doi.org/10.1007/s11356-021-16339-3 | |
dc.description.abstract | Chemical compounds produced by humans are continuously reaching the environment. In this work, we characterised the expression patterns of important endocrine-related genes involved in the ecdysone pathway in the fourth larval instar of the model species Chironomus riparius after exposure to three chemicals: ethinyl oestradiol (EE), nonylphenol (NP) and bis(tributyltin) oxide (TBTO). We used real-time PCR to analyse the gene expression levels of ecdysone receptor (EcR) and ultraspiracle (usp), two genes that encode the dimerising partners of the functional ecdysone receptor; the orphan receptor ERR (oestrogen-related receptor), with an unknown function in invertebrates; and E74, an early response gene induced by ecdysteroids. We estimated the bioaccumulation potential, bioavailability and physicochemical properties of these chemicals, together with a number of other exogenous agents known to interfere with the hormonal system. We also provide a review of previous transcriptional studies showing the effect of all these chemicals on ecdysone cascade genes. This analysis provides useful data for future ecotoxicological studies involving invertebrate species. | en |
dc.description.version | versión publicada | |
dc.identifier.citation | de la Fuente, ., Folgar, R.M., Martínez-Paz, P. et al. Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius. Environ Sci Pollut Res 29, 10210–10221 (2022). https://doi.org/10.1007/s11356-021-16339-3 | |
dc.identifier.doi | https://doi.org/10.1007/s11356-021-16339-3 | |
dc.identifier.issn | 1614-7499 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14468/23892 | |
dc.journal.title | Environmental Science and Pollution Research | |
dc.journal.volume | 29 | |
dc.language.iso | en | |
dc.page.final | 10221 | |
dc.page.initial | 10210 | |
dc.publisher | Springer | |
dc.relation.center | Facultades y escuelas::Facultad de Ciencias | |
dc.relation.department | Física Matemática y de Fluídos | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.es | |
dc.subject | 24 Ciencias de la Vida | |
dc.subject.keywords | endocrine-disrupting chemicals (EDCs) | en |
dc.subject.keywords | chironomus riparius | en |
dc.subject.keywords | toxicity | en |
dc.subject.keywords | transcriptional response | en |
dc.title | Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius | en |
dc.type | artículo | es |
dc.type | journal article | en |
dspace.entity.type | Publication | |
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relation.isAuthorOfPublication | 59242022-038d-4a1f-9c1a-bdfdb492beed | |
relation.isAuthorOfPublication | a078395f-9ae2-4e6a-b18c-2549d07bdea9 | |
relation.isAuthorOfPublication | 700f9417-c7b6-45f0-a781-3b1b8ae73b9c | |
relation.isAuthorOfPublication.latestForDiscovery | a76eecec-72a7-45d9-aff0-5a76e0351dd8 |
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