Fecha
2024-09-19
Editor/a
Director/a
Tutor/a
Coordinador/a
Prologuista
Revisor/a
Ilustrador/a
Derechos de acceso
info:eu-repo/semantics/openAccess
Título de la revista
ISSN de la revista
Título del volumen
Editor
AccScience Publishing
Citas
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Resumen
Functional neurological disorder (FND), or conversion disorder, is a psychosomatic condition that affects the voluntary motor and/or sensory functions of the patient. Its origin is not yet fully understood, but the main risk factors related to this disorder include exposure to recent psychological stressors and previous experience of aversive episodes during childhood, such as abuse, family dysfunction, and neglect. The symptoms of FND result from complex interactions involving the central nervous system and also the endocrine and immune systems. In this work, we hypothesized the relationship between the gut microbiome and the pathophysiology of FND because both share several common features, such as the effects of neurotransmitters, the hippocampal expression of brain-derived neurotrophic factor, and the inflammatory responses. Based on these common aspects, we suggested that stress, gut microbiome, and inflammation factors induce chronic and systemic inflammation of the brain causing neurological disorders, including FND. More specific studies are warranted to validate the casual or causal relationship between FND and the gut microbiome.
Descripción
The registered version of this article, first published in “Journal of Clinical and Basic Psychosomatics, 2, 2024", is available online at the publisher's website: AccScience Publishing, https://doi.org/10.36922/jcbp.4160
La versión registrada de este artículo, publicado por primera vez en “Journal of Clinical and Basic Psychosomatics, 2, 2024", está disponible en línea en el sitio web del editor: AccScience Publishing, https://doi.org/10.36922/jcbp.4160
Categorías UNESCO
Palabras clave
functional neurological disorder, conversion disorder, gut microbiome, neurotransmitters, microbial metabolites, neuroinflammation
Citación
Borrego-Ruiz, A., & Borrego, J.J. (2024). Functional neurological disorder and gut microbiome: Casual or causal relationship?. Journal of Clinical and Basic Psychosomatics, 2(4), 4160. https://doi.org/10.36922/jcbp.4160
Centro
Facultad de Psicología
Departamento
Psicología Social y de las Organizaciones