Publicación:
Estrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats

Vista sencilla de ítem
dc.contributor.authorLagunas, Natalia
dc.contributor.authorMarraudino, Marilena
dc.contributor.authorAmorim, Miguel de
dc.contributor.authorPinos Sánchez, María Elena
dc.contributor.authorCollado Guirao, Paloma
dc.contributor.authorPanzica, GianCarlo
dc.contributor.authorGarcia Segura, Luis
dc.contributor.authorGrassi, Daniela
dc.date.accessioned2025-01-08T12:27:38Z
dc.date.available2025-01-08T12:27:38Z
dc.date.issued2019-06-01
dc.descriptionEste es el manuscrito aceptado del artículo. La versión registrada fue publicada por primera vez en Brain Research, Volume 1712, 2019, Pages 93-100, está disponible en línea en el sitio web del editor: https://doi.org/10.1016/j.brainres.2019.02.002. This is the accepted manuscript of the article. The copyrighted version was first published in Brain Research, Volume 1712, 2019, Pages 93-100, and is available online at the publisher's website: https://doi.org/10.1016/j.brainres.2019.02.002 .
dc.description.abstractThe ovarian hormone 17β-estradiol is known to regulate the release, expression and immunoreactivity of arginine-vasopressin (AVP) in the supraoptic and paraventricular hypothalamic nuclei of rodents. Previous studies have shown that estrogen receptor α is involved in the effects of chronic estradiol administration on arginine-vasopressin immunoreactivity in the female rat hypothalamus. In this study we have examined the effect of an acute administration of estradiol or specific agonists for estrogen receptors α, β and G protein-coupled estrogen receptor 1 on the immunoreactivity of arginine-vasopressin in the hypothalamus of adult ovariectomized female rats. Acute estradiol administration resulted in a significant decrease in the number of arginine-vasopressin immunoreactive neurons in the supraoptic and paraventricular nuclei after 24 h. The effects of the specific estrogen receptors agonists suggest that the action of estradiol on arginine-vasopressin immunoreactivity is mediated in the supraoptic nucleus by G protein-coupled estrogen receptor 1 and in the paraventricular nucleus by both estrogen receptor β and G protein-coupled estrogen receptor 1. Thus, in contrast to previous studies on the effect of chronic estrogenic treatments, the present findings suggest that estrogen receptor β and G protein-coupled estrogen receptor 1 mediate the acute effects of estradiol on arginine-vasopressin immunoreactivity in the hypothalamus of ovariectomized rats.en
dc.description.versionversión final
dc.identifier.citationNatalia Lagunas, Marilena Marraudino, Miguel de Amorim, Helena Pinos, Paloma Collado, GianCarlo Panzica, Luis M. Garcia-Segura, Daniela Grassi, Estrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats, Brain Research, Volume 1712, 2019, Pages 93-100, ISSN 0006-8993, https://doi.org/10.1016/j.brainres.2019.02.002
dc.identifier.doihttps://doi.org/10.1016/j.brainres.2019.02.002
dc.identifier.issn0006-8993; e-ISSN: 1872-6240
dc.identifier.urihttps://hdl.handle.net/20.500.14468/25129
dc.journal.titleBrain Research
dc.journal.volume1712
dc.language.isoen
dc.page.final100
dc.page.initial93
dc.publisherElsevier
dc.relation.centerFacultades y escuelas::Facultad de Psicología
dc.relation.departmentPsicobiología
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject61 Psicología
dc.subject.keywords17β-estradiolen
dc.subject.keywordsGPERen
dc.subject.keywordsPPTen
dc.subject.keywordsDPNen
dc.subject.keywordsG1en
dc.subject.keywordsHypothalamusen
dc.titleEstrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female ratsen
dc.typeartículoes
dc.typejournal articleen
dspace.entity.typePublication
relation.isAuthorOfPublication71657c77-6882-40f7-a5c9-03b3da3a0f26
relation.isAuthorOfPublication1c9559e7-aba1-4505-8acb-8a3813368a63
relation.isAuthorOfPublication.latestForDiscovery71657c77-6882-40f7-a5c9-03b3da3a0f26
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Estrogen-receptor-beta_Lagunas-et-al.pdf
Tamaño:
2.14 MB
Formato:
Adobe Portable Document Format
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
3.62 KB
Formato:
Item-specific license agreed to upon submission
Descripción:
Descargar
Colecciones
Artículos y papers