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3D-printed Transmembrane Glycoprotein Cancer Biomarker Aptasensor

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dc.contributor.authorGonzález Crevillén, Agustín
dc.contributor.authorMayorga Martinez, Carmen C.
dc.contributor.authorZelenka, Jaroslav
dc.contributor.authorRimpelová, Silvie
dc.contributor.authorRuml, Tomáš
dc.contributor.authorPumera, Martin
dc.date.accessioned2024-10-07T11:08:14Z
dc.date.available2024-10-07T11:08:14Z
dc.date.issued2021-08-21
dc.descriptionEste es el manuscrito aceptado del artículo. La versión registrada fue publicada por primera vez en Elsevier, Applied Materials Today, Volume 24, 2021, 101153, ISSN 2352-9407, está disponible en línea en el sitio web del editor: https://doi.org/10.1016/j.apmt.2021.101153. This is the accepted manuscript of the article. The Version of Record was first published in Elsevier, Applied Materials Today, Volume 24, 2021, 101153, ISSN 2352-9407, is available online at the publisher's website: https://doi.org/10.1016/j. apmt.2021.101153.
dc.description.abstractPoint-of-care, easy to manufacture, and low cost detection of cancer biomarkers is crucial for fighting the early stage disease. 3D printing allows delocalized printing at remote locations with updates/upgrades available globally via electronic files. Mucin 1 (MUC1) is a protein that is overexpressed in a number of epithelial cancers and is a key factor in advancement of the disease. Here we show the simple point-of-care 3D printing fabrication of a MUC1 aptasensor using a nanocarbon/polymer filament. Efficacy of the 3D-printed aptasensor is demonstrated by monitoring the expression and release of MUC1 in breast cancer cell cultures. Such a simple, low cost, and easy to locally fabricate cancer biosensor will have a large impact on the field of cancer diagnostics.en
dc.description.versionversión final
dc.identifier.citationAgustín G. Crevillen, Carmen C. Mayorga-Martinez, Jaroslav Zelenka, Silvie Rimpelová, Tomáš Ruml, Martin Pumera, 3D-printed transmembrane glycoprotein cancer biomarker aptasensor, Applied Materials Today, Volume 24, 2021, 101153, ISSN 2352-9407, https://doi.org/10.1016/j.apmt.2021.101153.
dc.identifier.doihttps://doi.org/10.1016/j.apmt.2021.101153
dc.identifier.issn2352-9407
dc.identifier.urihttps://hdl.handle.net/20.500.14468/23938
dc.journal.titleApplied Materials Today
dc.journal.volume24
dc.language.isoen
dc.publisherElsevier
dc.relation.centerFacultades y escuelas::Facultad de Ciencias
dc.relation.departmentCiencias Analíticas
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject23 Química
dc.subject.keywordsAdditive manufacturingen
dc.subject.keywordsAptameren
dc.subject.keywordsBreast cancer cellsen
dc.subject.keywordsBiomarkeren
dc.subject.keywordsSensoren
dc.title3D-printed Transmembrane Glycoprotein Cancer Biomarker Aptasensoren
dc.typeartículoes
dc.typejournal articleen
dspace.entity.typePublication
relation.isAuthorOfPublication0f39284a-d95a-443a-bb2e-21297ec40b76
relation.isAuthorOfPublication.latestForDiscovery0f39284a-d95a-443a-bb2e-21297ec40b76
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