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Enhanced preprocessing and adaptive weighted loss function for improved for white matter hyperintensity segmentation with convolutional neural networks.

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2020-10-06
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info:eu-repo/semantics/openAccess
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Universidad Nacional de Educación a Distancia (España). Escuela Técnica Superior de Ingeniería Informática. Departamento de Inteligencia Artificial.
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There is a great interest in automating White Matter Hyperintensities (WMH) segmentation due to their importance in the medical eld as well as the great amount of inter- and intra-observer variability that appears when it is manually segmented in magnetic resonance imaging. In this work we present a multistep tailored preprocessing consisting mainly of brain extraction, intensity contrast enhancement, subject based slice cropping and intensity standardization. The segmentation task is then performed by a fully convolutional neural network with attention gates which employs a customized loss function based on the dice similarity coecient and the F1 score. Experimental results on the white matter hyperintensities segmentation challenge [Kuijf et al., 2019] show that our proposed preprocessing improves segmentation, that attention gated U-Net further improves segmentation tasks compared to the original U-Net and our proposed loss function has the potential to improve lesion-wise F1 on DSC based segmentations.
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Facultades y escuelas::E.T.S. de Ingeniería Informática
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Inteligencia Artificial
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