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Ordered mesoporous molecular sieves as active catalyts for the synthesis of 1,4-dihydropyridine derivatives

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dc.contributor.authorCalvino Casilda, Vanesa
dc.contributor.authorMartín Aranda, Rosa María
dc.date.accessioned2024-05-20T11:58:06Z
dc.date.available2024-05-20T11:58:06Z
dc.date.issued2020-09-01
dc.description.abstractResearch on heterocyclic compounds with biological and pharmacological activity continues to arouse great interest. The study of 1,4-dihydropyridines (1,4-DHPs) is of particular interest in the pharmaceutical field due to their important applications as calcium channel antagonists for the treatment of heart diseases. The implementation of novel heterogeneous catalysts to optimize Hantzsch synthesis, such as ordered mesoporous molecular sieves, is an efficient and eco-friendly proposal that still requires a lot of work. The remarkable features of ordered mesoporous molecular sieves, such as high surface area, tailored porosity, chemical and thermal stability, among others, turn these materials into powerful solid catalysts capable of selectively leading the synthesis of 1,4-DHPs. In addition, the combination of ordered mesoporous molecular sieves and process intensification for the synthesis of 1,4-DHP derivatives is still a research field in development. Therefore, promote greener methodologies in the synthesis of 1,4-DHPs that can be extended to any organic synthesis in fine chemical production is an important goal yet to be achieved.en
dc.description.versionversión publicada
dc.identifier.doihttp://doi.org/10.1016/j.cattod.2019.06.046
dc.identifier.issn1873-4308
dc.identifier.urihttps://hdl.handle.net/20.500.14468/12768
dc.journal.titleCatalysis Today
dc.journal.volume354
dc.language.isoen
dc.publisherElsevier
dc.relation.centerFacultad de Ciencias
dc.relation.departmentQuímica Inorgánica y Química Técnica
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject.keywordsOrdered mesoporous molecular sieves
dc.subject.keywordsHeterogeneous catalysis
dc.subject.keywordsHeterocyclic scaffolds
dc.subject.keywords1,4-Dihydropyridines
dc.titleOrdered mesoporous molecular sieves as active catalyts for the synthesis of 1,4-dihydropyridine derivativeses
dc.typejournal articleen
dc.typeartículoes
dspace.entity.typePublication
relation.isAuthorOfPublication2c001973-924e-4c7c-a0b0-246e6b9a778e
relation.isAuthorOfPublicationbafbca28-7ba9-4a29-b350-ebdcbc2381bb
relation.isAuthorOfPublication.latestForDiscovery2c001973-924e-4c7c-a0b0-246e6b9a778e
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