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Placebo trials without mechanisms: How far can they go?

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dc.contributor.authorTeira Serrano, David
dc.date.accessioned2024-05-21T12:53:12Z
dc.date.available2024-05-21T12:53:12Z
dc.date.issued2019-07-01
dc.description.abstractIn this paper, I suggest that placebo effects, as we know them today, should be understood as experimental phenomena, low-level regularities whose causal structure is grasped through particular experimental designs with little theoretical guidance. Focusing on placebo interventions with needles for pain reduction -one of the few placebo regularities that seems to arise in meta-analytical studies- I discuss the extent to which it is possible to decompose the different factors at play through more fine-grained randomized clinical trials. My sceptical argument is twofold. On the one hand, I argue that experiments alone are not enough to standardize interventions, and that it is necessary to include theories. On the other hand, I argue that the social interactions that seem to be part of placebo effects are difficult, if not impossible, to blind. Therefore, the measurement biases arising from the participants’ reactivity to the experimental setup cannot be controlled for. Further decomposition of placebo effects requires a theoretical account of the existing experimental regularities that may guide further tests.en
dc.description.versionversión final
dc.identifier.doihttps://doi.org/10.1016/j.shpsc.2019.101177
dc.identifier.urihttps://hdl.handle.net/20.500.14468/19415
dc.journal.titleStudies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
dc.language.isoen
dc.relation.centerFacultad de Filosofía
dc.relation.departmentLógica, Historia y Filosofía de la Ciencia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject.keywordsplacebo
dc.subject.keywordsclinical trials
dc.subject.keywordsreactivity
dc.subject.keywordsneedling
dc.subject.keywordsmechanisms
dc.subject.keywordsstandardization
dc.titlePlacebo trials without mechanisms: How far can they go?es
dc.typejournal articleen
dc.typeartículoes
dspace.entity.typePublication
relation.isAuthorOfPublicationad2bda75-c33c-48e1-aad8-c7eb3cfc04cb
relation.isAuthorOfPublication.latestForDiscoveryad2bda75-c33c-48e1-aad8-c7eb3cfc04cb
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