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2025-03-25
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info:eu-repo/semantics/openAccess
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Open Exploration
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Resumen
Ketogenic diets are emerging dietary patterns that have demonstrated potential as therapeutic tools in a variety of symptoms and conditions, such as epileptic seizures, diabetes, obesity, cancer, migraines, and metabolic syndrome. This narrative review examines the therapeutic effects of ketogenic diets on physiological and mental health, including their role in modulating the gut microbiome. Ketogenic diets promote weight loss, enhance insulin sensitivity, and may lower dyslipidemia, which are crucial factors in preventing cardio-metabolic diseases. They also play a significant role in the composition and function of the gut microbiome, serving as a therapeutic approach to control autoimmune diseases, given their effectiveness in reducing pro-inflammatory cells. Conversely, a potential downside of these diets is the decrease in beneficial bacteria that have been positively associated with human health. Regarding mental health, ketogenic diets have the capability to stabilize neural networks, improve neuroplasticity, and exert direct benefits in brain bioenergetics, thereby potentially alleviating the symptoms related to several mental conditions, such as epilepsy, anxiety, depression, schizophrenia, bipolar disorder, autism spectrum disorder, and certain neurodegenerative diseases. However, more randomized, long-term studies are required to assess their efficacy, sustainability, and safety, including methodological rigor to strengthen findings on dietary impacts.
Descripción
The registered version of this article, first published in “Exploration of Foods and Foodomics, 3, 2025", is available online at the publisher's website: Open Exploration, https://doi.org/10.37349/eff.2025.101079
La versión registrada de este artículo, publicado por primera vez en “Exploration of Foods and Foodomics, 3, 2025", está disponible en línea en el sitio web del editor: Open Exploration, https://doi.org/10.37349/eff.2025.101079
Categorías UNESCO
Palabras clave
ketogenic diets, physiological disorders, mental disorders, gut microbiome, therapeutic tool
Citación
Borrego-Ruiz A, Borrego JJ. Therapeutic effects of ketogenic diets on physiological and mental health. Exploration of Foods and Foodomics. 2025;3:101079. https://doi.org/10.37349/eff.2025.101079
Centro
Facultad de Psicología
Departamento
Psicología Social y de las Organizaciones