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Effectiveness of interventions to prevent perinatal depression: An umbrella review of systematic reviews and meta-analysis.

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dc.contributor.authorMotrico, Emma
dc.contributor.authorBina, Rena
dc.contributor.authorKassianos, Angelos P.
dc.contributor.authorMateus, Vera
dc.contributor.authorOzteki, Deniz
dc.contributor.authorRodríguez Muñoz, María de la Fe
dc.contributor.authorMoreno Peral, Patricia
dc.contributor.authorConejo Cerón, Sonia
dc.contributor.authorLe, Huynh-Nhu
dc.date.accessioned2024-07-29T15:36:47Z
dc.date.available2024-07-29T15:36:47Z
dc.date.issued2023-03-15
dc.descriptionThe registered version of this article, first published in General Hospital Psychiatry, is available online at the publisher's website: Elsevier, https://doi.org/10.1016/j.genhosppsych.2023.03.007
dc.descriptionLa versión registrada de este artículo, publicado por primera vez en General Hospital Psychiatry, está disponible en línea en el sitio web del editor: Elsevier, https://doi.org/10.1016/j.genhosppsych.2023.03.007
dc.description.abstractBackground: To date, dozens of systematic reviews (SRs) and meta-analyses (MAs) summarize the effectiveness of preventive interventions for perinatal depression. However, the results are inconclusive, making an urgent need to step up to higher levels of evidence synthesis. Aims: To summarize and compare the evidence from the SR&MA examining the effectiveness of all types of interventions for preventing perinatal depression. Method: PubMed, PsycINFO, Cochrane Database of Systematic Reviews and OpenGrey were searched from inception to December 2022. We selected SR&MA of randomized controlled trials (RCTs) that compared all types of preventive interventions for perinatal depression with control groups whose outcome was the reduction of depressive symptoms and/or incidence of new cases of perinatal depression (PROSPERO: CRD42020173125). Results: A total of 19 SRs and MAs evaluated 152 unique RCTs that included 83,408 women from 26 countries and five continents. The median effect size for any intervention was SMD = 0.29 (95% CI: 0.20 to 0.38). Exercise/physical activity-based, psychological, and any type of intervention showed median effect sizes of 0.43, 0.28 and 0.36, respectively. The degree of overlap among RCTs was slight. According to AMSTAR-2, 79% of them were rated as low or critically low-quality. The strength of evidence, according to GRADE, was poorly reported and, in most cases, was low. Conclusions: Exercise/physical activity-based and psychological interventions have a small-to-medium effect on reducing perinatal depressive symptoms. There is insufficient evidence to conclude that dietary supplements and pharmacological interventions are effective in preventing perinatal depression. There is a need for high-quality SR&MA of RCTs, mainly focusing on universal preventive interventionses
dc.description.versionversión publicada
dc.identifier.citationMotrico, E., Bina, R., Kassianos, A. P., Le, H. N., Mateus, V., Oztekin, D., Rodriguez-Muñoz, M. F., Moreno-Peral, P., & Conejo-Cerón, S. (2023). Effectiveness of interventions to prevent perinatal depression: An umbrella review of systematic reviews and meta-analysis. General Hospital Psychiatry, 82, 47–61. https://doi.org/10.1016/j.genhosppsych.2023.03.007
dc.identifier.doihttps://doi.org/10.1016/j.genhosppsych.2023.03.007
dc.identifier.issn0163-8343
dc.identifier.urihttps://hdl.handle.net/20.500.14468/23145
dc.journal.titleGeneral Hospital Psychiatry
dc.journal.volume82
dc.language.isoen
dc.page.final61
dc.page.initial47
dc.publisherElsevier
dc.relation.centerFacultades y escuelas::Facultad de Psicología
dc.relation.departmentPsicología de la Personalidad, Evaluación y Tratamiento Psicológico
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subject61 Psicología
dc.subject.keywordsperinatal depressionen
dc.subject.keywordspreventionen
dc.subject.keywordsrandomized control trialen
dc.subject.keywordssystematic reviewen
dc.subject.keywordsmeta-analysisen
dc.titleEffectiveness of interventions to prevent perinatal depression: An umbrella review of systematic reviews and meta-analysis.en
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dc.typejournal articleen
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoverydf2e33fa-76fc-4279-b09f-08fbeb59a7e0
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