Publicación:
Hematic Antegrade Repriming Reduces Emboli on Cardiopulmonary Bypass: A Randomized Controlled Trial

Vista sencilla de ítem
dc.contributor.authorBlanco Morillo, Juan
dc.contributor.authorSalmerón Martínez, Diego
dc.contributor.authorMorillo Cuadrado, Daniel Vicente
dc.contributor.authorArribas Leal, Jose María
dc.contributor.authorPuis, Luc
dc.contributor.authorVerdú Verdú, Alicia
dc.contributor.authorMartínez Molina, Mercedes
dc.contributor.authorTormos Ruiz, Encarnación
dc.contributor.authorSornichero Caballero, Angel
dc.contributor.authorRamírez Romero, Pablo
dc.contributor.authorFarina, Piero
dc.contributor.authorCánovas López, Sergio
dc.contributor.authorMorillo Cuadrado, Daniel Vicente
dc.date.accessioned2024-12-05T11:02:29Z
dc.date.available2024-12-05T11:02:29Z
dc.date.issued2023-03
dc.descriptionLa versión registrada de este artículo, publicado por primera vez en ASAIO Journal, 69(3), 324., está disponible en línea en el sitio web del editor: https://doi.org/10.1097/MAT.0000000000001776 The registered version of this article, first published in ASAIO Journal, 69(3), 324., is available online at the publisher's website: https://doi.org/10.1097/MAT.0000000000001776
dc.description.abstractParticulate and gaseous microemboli (GME) are side effects of cardiac surgery that interfere with postoperative recovery by causing endothelial dysfunction and vascular blockages. GME sources during surgery are multiple, and cardiopulmonary bypass (CPB) is contributory to this embolic load. Hematic antegrade repriming (HAR) is a novel procedure that combines the benefits of repriming techniques with additional measures, by following a standardized procedure to provide a reproducible hemodilution of 300 ml. To clarify the safety of HAR in terms of embolic load delivery, a prospective and controlled study was conducted, by applying Doppler probes to the extracorporeal circuit, to determine the number and volume of GME released during CPB. A sample of 115 patients (n = 115) was considered for assessment. Both groups were managed under strict normothermia, and similar clinical conditions and protocols, receiving the same open and minimized circuit. Significant differences in GME volume delivery (control group [CG] = 0.28 ml vs. HAR = 0.08 ml; p = 0.004) and high embolic volume exposure (>1 ml) were found between the groups (CG = 30.36% vs. HAR = 4.26%; p = 0.001). The application of HAR did not represent an additional embolic risk and provided a four-fold reduction in the embolic volume delivered to the patient (coefficient, 0.24; 95% CI, 0.08–0.72; p = 0.01), which appears to enhance GME clearance of the oxygenator before CPB initiation.en
dc.description.versionversión publicada
dc.identifier.citationBlanco-Morillo, J., Salmerón Martínez, D., Morillo-Cuadrado, D. V., Arribas-Leal, J. M., Puis, L., Verdú-Verdú, A., Martínez-Molina, M., Tormos-Ruiz, E., Sornichero-Caballero, A., Ramírez-Romero, P., Farina, P., & Cánovas-López, S. (2023). Hematic Antegrade Repriming Reduces Emboli on Cardiopulmonary Bypass: A Randomized Controlled Trial. ASAIO Journal, 69(3), 324. https://doi.org/10.1097/MAT.0000000000001776
dc.identifier.doihttps://doi.org/10.1097/MAT.0000000000001776
dc.identifier.issn1058-2916; eISSN: 1538-943X
dc.identifier.urihttps://hdl.handle.net/20.500.14468/24720
dc.journal.issue3
dc.journal.titleASAIO Journal
dc.journal.volume69
dc.language.isoen
dc.publisherLippincott, Williams & Wilkins
dc.relation.centerFacultades y escuelas::Facultad de Psicología
dc.relation.departmentMetodología de las Ciencias del Comportamiento
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject61 Psicología
dc.subject.keywordscardiac surgeryen
dc.subject.keywordscardiopulmonary bypassen
dc.subject.keywordsextracorporeal circuitsen
dc.subject.keywordsgaseous microembolien
dc.subject.keywordshematic antegrade reprimingen
dc.subject.keywordspulsed Doppleren
dc.titleHematic Antegrade Repriming Reduces Emboli on Cardiopulmonary Bypass: A Randomized Controlled Trialen
dc.typeartículoes
dc.typejournal articleen
dspace.entity.typePublication
relation.isAuthorOfPublicationeaf86785-e049-4e6e-a3cc-0409c8954333
relation.isAuthorOfPublication.latestForDiscoveryeaf86785-e049-4e6e-a3cc-0409c8954333
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
MorilloCuadrado_Daniel_Hematic_Antegrade_Repr.pdf
Tamaño:
733.06 KB
Formato:
Adobe Portable Document Format
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
3.62 KB
Formato:
Item-specific license agreed to upon submission
Descripción:
Descargar
Colecciones
Artículos y papers