Persona:
Domínguez Sánchez, Francisco Javier

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Domínguez Sánchez
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Francisco Javier
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2005 - 200912010 - 201912020 - 20232
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Mostrando 1 - 4 de 4
  • Miniatura
    Publicación
    N-acetyl-aspartate levels in the dorsolateral prefrontal cortex in the early years of schizophrenia are inversely related to disease duration.
    (Elsevier, 2005-03-01) Molina, Vicente; Reig Redondo, Santiago; Benito, Carlos; Pascau González-Garzón, Javier; Sarramea, Fernando; Gispert, Juan Domingo; Misiego, José M.; Palomo, Tomás; Desco, Manuel; Domínguez Sánchez, Francisco Javier; Sanz Pérez, Javier; Santa Marta Pastrana, Cristina María
    Magnetic resonance spectroscopy studies in schizophrenia have revealed consistently reduced N-acetyl aspartate (NAA) levels in chronic patients, but not in recent-onset patients. Studies on the relationship between this marker and disease duration have commonly been negative, although it is also true that they have been conducted in patients with long-standing disease. We compared NAA levels in the dorsolateral prefrontal cortex in 16 recent-onset patients (duration: 1.8±0.6 years), 19 chronic patients (duration: 9.7±6.1 years), and 20 healthy controls. We studied the NAA/creatine and choline/creatine ratios in the dorsolateral prefrontal cortex in both hemispheres, controlling for the effect of age. Chronic patients had significantly lower NAA/Cr ratios in the left hemisphere compared to recent-onset patients and healthy controls, with no difference in Cho/Cr ratio. There were no differences between controls and recent-onset patients. There was a significant inverse relationship between left-side NAA/Cr and disease duration, suggesting that prefrontal NAA levels may progressively decrease in schizophrenia. Taken within the context of the existing literature, these results indicate that this process may be limited to the early years following the onset of the disease. Therefore, reduced prefrontal levels of NAA may be limited to chronic schizophrenia patients.
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    Publicación
    La evaluación en neuropsicología forense
    (Sanz y Torres, 2020) Domínguez Sánchez, Francisco Javier
  • Miniatura
    Publicación
    Relationship between adult attachment and cognitive emotional regulation style in women and men
    (Nature Research, 2023-05-19) Delgado Egido, Begoña; Amor Andrés, Pedro Javier; Domínguez Sánchez, Francisco Javier; Holgado Tello, Francisco Pablo
    Cognitive emotion regulation (CER) strategies are useful in evaluating the risk of developing emotional disorders and that they may define subjects’ styles. This study aims to explore the extent to which specific styles of CER strategies relate to the anxious and avoidant attachment dimensions in adults and whether such relationships operate similarly for women and men. Two hundred and fifteen adults (between 22 and 67 years old) completed the Spanish versions of the Cognitive Emotion Regulation Questionnaire and the Experiences in Close Relationships instrument. Cluster analysis, ANOVA and Student's t-test were used. Our results show that women and men can be successfully classified into two CER clusters (Protective and Vulnerable), distinguished by the higher use in the protective cluster of the CER strategies considered most adaptive and complex (Acceptance, Positive Refocusing, Refocus on Planning, Positive Reappraisal, and Putting into Perspective). However, only in women were the anxious and avoidant attachment dimensions significantly associated with CER style. In conclusion, from a clinical and interpersonal perspective, it is interesting to be able to predict the belonging to a Protective or Vulnerable coping style by analysing the CER strategies and to know their relationship with the adult affective system.
  • Miniatura
    Publicación
    Sesgo De Evitación De Información Emocional Positiva En La Tristeza
    (Sociedad Española para el Estudio de la Ansiedad y el Estrés, 2013) García Fernández-Abascal, Enrique; Martín Díaz, María Dolores; Domínguez Sánchez, Francisco Javier
    En este trabajo se estudian los déficits específicos y generalizados en el reconocimiento de la expresión emocional facial y vocal entre personas con baja y alta tristeza. Se pretende verificar si los sesgos que aparecen en el caso del trastorno por depresión mayor se producen de igual manera en condiciones emocionales no clínicas. Los resultados muestran que no se producen déficits generalizados en el reconocimiento emocional, pero sí se da el sesgo de evitación de información emocional positiva. En el caso del reconocimiento vocal también aparece un sesgo que determina mayor exactitud en el reconocimiento de la expresión de tristeza en el grupo de alta tristeza. Ambos sesgos parecen ser fenómenos independientes ya que no ocurren en el caso del reconocimiento facial y la correlación entre ambos no es significativa.