Examinando por Autor "Falomir Ventura, Eva"
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Publicación Colaboraciones en Química: Diseño de compuestos anticáncer multidiana(Universidad Nacional de Educación a Distancia (España). Facultad de Ciencias, 2018-01-01) Falomir Ventura, EvaPublicación Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes(Wiley, 2016-07) Martí Centelles, Rosa; Falomir Ventura, Eva; Carda, Miguel; Nieto Gómez, Carla Isabel; Cornago, Mª del PilarA group of 13 curcuminoid pyrazoles was investigated for their cytotoxicity on three tumoral cell lines (HT-29, MCF-7, and HeLa) and one non-tumoral human cell line (HEK-293). The values obtained were compared with those of curcumin. A subset of selected derivatives was also studied for their ability to downregulate expression of the hTERT and c-Myc genes, which are both involved in telomerase activity.