Persona: Teira Serrano, David
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Teira Serrano
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David
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Publicación Blinding and the non-interference assumption in medical and social trials(2012-12-25) Teira Serrano, DavidIn this paper, I am going to present and defend the following claims. First, if the participants are not indifferent regarding treatments, we need to implement a blinding device in every trial in order to ground the Non Interference Assumption. But we cannot take its efficacy for granted: we need to test that the blinding actually controlled for the expectations of the participants and no malign unmasking spoiled the NIA. Precisely because this test is necessary, we can only blind the participants up to a certain point: we cannot deceive them. There is evidence showing that if they suspect they are being deceived, they will deviate from the trial protocol, flawing the outcome.Publicación On the limits of cultural relativism as a debiasing method(2021-01-01) Teira Serrano, DavidI analyse cultural relativism as a methodological strategy to correct for ethnocentric biases in anthropological fieldwork. I discuss the format debiasing norms may adopt (rules or standards) depending on whether a discipline has a causal or interpretative outlook. Boas and his school advocated for an interpretative approach to ethnographic fieldwork, in which cultural relativism was implemented as a standard (“Only culturally unbiased reports are admissible”) to be interpreted by expert third parties. Legitimate as it may be as a debiasing method, it does not allow anthropologists to adjudicate their debates on biases in their ethnographic record.Publicación Etica o economía : Philippe van Parijs y la renta básica(2003-02-22) Teira Serrano, DavidLa renta básica se nos presenta en la obra de Philippe van Parijs como una propuesta política filosóficamente argumentada, de modo tal que convencerá tanto al teórico de la justicia como al ciudadano que votará su implantación. En este artículo analizamos la argumentación de van Parijs mostrando cómo la efectividad política de sus tesis sólo se sostiene a costa de reducir el debate sobre la renta básica a los términos de su propia concepción de la ética. Ponemos en duda, por nuestra parte, el alcance de esta reducción sobre un doble plano: diluye por completo la dimensión prudencial de toda argumentación política, y no deja más alternativa que la educación sentimental para quienes no se dejen convencer por el equilibrio reflexivo.Publicación Cómo mide el riesgo el observador imparcial(2015) Heras Martínez, Antonio José; Teira Serrano, DavidExploramos aquí la conexión entre los conceptos de riesgo e igualdad en el argumento del observador imparcial. La concepción de la justicia que elegiría un observador imparcial se justifica por la pureza del procedimiento de elección. Sin embargo, si modelizamos esta decisión utilizando medidas del riesgo habituales en matemática financiera, veremos cómo el criterio de elección del observador bajo el velo de la ignorancia contiene una preferencia implícita por el grado de desigualdad resultante. Esto nos obliga a reconsiderar la pureza procedimental de la elección.Publicación Disease-mongering through clinical trials(2015) González Moreno, María; Saborido Alejandro, Cristian; Teira Serrano, DavidOur goal in this paper is to articulate a precise concept of at least a certain kind of disease-mongering, showing how pharmaceutical marketing can commercially exploit certain diseases when their best definition is given through the success of a treatment in a clinical trial. We distinguish two types of disease-mongering according to the way they exploit the definition of the trial population for marketing purposes. We argue that behind these two forms of disease-mongering there are two well-known problems in the statistical methodology of clinical trials (the reference class problem and the distinction between statistical and clinical significance). Overcoming them is far from simplePublicación Choosing expert statistical advice: practical costs and epistemic justificationGonzález de Prado Salas, Javier; Teira Serrano, DavidWe discuss the role of practical costs in the epistemic justification of a novice choosing expert advice, taking as a case study the choice of an expert statistician by a lay politician. First, we refine Goldman’s criteria for the assessment of this choice, showing how the costs of not being impartial impinge on the epistemic justification of the different actors involved in the choice. Then, drawing on two case studies, we discuss in which institutional setting the costs of partiality can play an epistemic role. This way we intend to show how the sociological explanation of the choice of experts can incorporate its epistemic justification.Publicación Facts, Norms and Expected Utility Functions(2008-05-15) Jallais, Sophie; Pradier, Pierre Charles; Teira Serrano, DavidIn this paper we want to explore an argumentative pattern that provides a normative justification for expected utility functions grounded on empirical evidence, showing how it worked in three different episodes of their development. The argument claims that we should prudentially maximize our expected utility since this is the criterion effectively applied by those who are considered wisest in making risky choices (be it gamblers or businessmen). Yet, to justify the adoption of this rule, it should be proven that this is empirically true: i.e., that a given function allows us to predict the choices of that particular class of agents. We show how expected utility functions were introduced and contested in accordance with this pattern in the 18th century and how it recurred in the 1950s when M. Allais made his case against the neobernoulliansPublicación Reseña de Hasok Chang, Inventing Temperature(2008-05-15) Teira Serrano, DavidReseña de CHANG, Hasok (2004): Inventing Temperature. Measurement and Scientific Progress. New York: Oxford University Press. Publicada en Theoria Vol. 21/3 – n. 57 – septiembre 2006Publicación Is the Genie Out of the Bottle? Digital Platforms and the Future of Clinical Trials(2019-01-01) Tempini, Niccolo; Teira Serrano, DavidIs it possible to conduct impartial clinical trials in a world full of digital networking tools that patients can use to coordinate themselves and act against research protocols? This paper builds on an ethnography of PatientsLikeMe, a company running an Internet social media network where patients with different conditions share their clinical data with standardised questionnaires. The company faced a serious dilemma in 2011 when some ALS patients, members of the site, started sharing data about a phase II clinical trial of an experimental drug (NP001) in which some of them were participating, to anticipate the experiment’s outcomes and understand each one’s allocation over trial arms. In parallel, some other patients were using the site and other web tools to coordinate and run their own replication of the trial with homebrew mixes of industrial grade chemicals. PatientsLikeMe researchers reflected on their position as networks managers and eventually decided to use the collected data to develop their own analysis of the efficacy of the original compound, and of the homebrewers’ compound. They presented the NP001 events as a case in point for articulating a new social contract for clinical research. This paper analyses these events, first, by understanding the clinical trial as an experiment organisation form that can succeed only as long as its protocol can be enforced; second, we observe how web networks make it dramatically easier for the trial protocol to be violated; finally, we point out how a potentially dangerous confluence of interests over web networks could incubate developments that disrupt the status quo without creating a robust and safe alternative for experimentation. We conclude by warning about the interests of the pharmaceutical industry in exploiting patients’ methodological requests to its own advantage.Publicación Milton Friedman, the Statistical Methodologist(2008-05-15) Teira Serrano, DavidIn this paper I study Milton Friedman’s statistical education, paying special attention to the different methodological approaches (Fisher, Neyman and Savage) to which he was exposed. I contend that these statistical procedures involved different views as to the evaluation of statistical predictions. In this light, the thesis defended in Friedman’s 1953 methodological essay appears substantially ungrounded.