Persona:
Calvino Casilda, Vanesa

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ORCID
0000-0002-2756-2164
Fecha de nacimiento
Proyectos de investigación
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Calvino Casilda
Nombre de pila
Vanesa
Nombre

Filtros

2020 - 20222
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Fecha de finalización: 2022 × Fecha de inicio: 2020 ×

Resultados de la búsqueda

Mostrando 1 - 2 de 2
  • Miniatura
    Publicación
    Ordered mesoporous molecular sieves as active catalyts for the synthesis of 1,4-dihydropyridine derivatives
    (Elsevier, 2020-09-01) Calvino Casilda, Vanesa; Martín Aranda, Rosa María
    Research on heterocyclic compounds with biological and pharmacological activity continues to arouse great interest. The study of 1,4-dihydropyridines (1,4-DHPs) is of particular interest in the pharmaceutical field due to their important applications as calcium channel antagonists for the treatment of heart diseases. The implementation of novel heterogeneous catalysts to optimize Hantzsch synthesis, such as ordered mesoporous molecular sieves, is an efficient and eco-friendly proposal that still requires a lot of work. The remarkable features of ordered mesoporous molecular sieves, such as high surface area, tailored porosity, chemical and thermal stability, among others, turn these materials into powerful solid catalysts capable of selectively leading the synthesis of 1,4-DHPs. In addition, the combination of ordered mesoporous molecular sieves and process intensification for the synthesis of 1,4-DHP derivatives is still a research field in development. Therefore, promote greener methodologies in the synthesis of 1,4-DHPs that can be extended to any organic synthesis in fine chemical production is an important goal yet to be achieved.
  • Miniatura
    Publicación
    Hierarchically organized metal supported carbon catalysts for C-C bond forming reactions
    (Elsevier, 2022-10-12) Martín García, Seila; Rubio Marcos, Fernando; Calvino Casilda, Vanesa
    The preparation of heterogeneous catalysts is decisive to the development of catalytic processes that are environmentally acceptable. Therefore, the methodology used in the preparation of such catalysts is a key factor in the development of high catalytic activity and with concern to environmental value. Herein, we report the design of catalysts by dispersing nanoparticles of cobalt oxide (Co 3O4 ) on micrometric supports of zinc oxide (ZnO) and activated carbon (AC) using a fast and green methodology free of waste and solvents and with a low-energy consumption. In particular, the partial reaction that takes place, at room temperature, between both metal oxides and between these oxides and AC, due to proximity and diffusion effects of the corresponding materials, results in the formation of different interfaces (ZnCo, ZnAC, CoAC Co-Co). Specifically, such interfaces are new reactive surfaces that lead to very interesting and innovative properties. Thus, depending on its application, it is possible to control and modify the catalytic properties (activity / conversion / selectivity) of a solid by tuning surface and interface. This fact is proved in the model reaction of Knoevenagel condensation between aldehydes and malonic esters. Therefore, our results prove that controlling the interfaces is a feasible way to achieve in the Knoevenagel condensation, which is a reaction widely used in the formation of C–C bonds for the organic synthesis of important intermediates and final products.