Silvia DortezMaria Cristina GonzálezGonzález Crevillén, AgustínAlberto Escarpa2024-10-032024-10-032021-08-29Silvia Dortez, Maria Cristina González, Agustín G. Crevillen, Alberto Escarpa, Gold nanostructure-related non-plasmon resonance absorption band as a fingerprint of ortho-alkyl substituted phenolic compounds, Microchemical Journal, Volume 171, 2021, 106788, ISSN 0026-265X, https://doi.org/10.1016/j.microc.2021.1067880026-265X; e-ISSN:1095-9149https://doi.org/10.1016/j.microc.2021.106788https://hdl.handle.net/20.500.14468/23884A systematic study for correlating the chemical structure of phenolic compounds with their capacity to form gold nanoparticles was carried out. Two groups of phenolic compounds were selected: one group with a substituent with different size at ortho position respect to hydroxyl group (phenol, o-cresol, 2-ethylphenol, 2-iso-propylphenol, 2-tert-butylphenol and 2-methoxyphenol); and the second group consists of phenolic compounds with the same substituent (methyl) at different positions respect to hydroxyl group (o-cresol, m-cresol and p-cresol). In addition to the characteristic gold nanoparticles (AuNPs) formation band at 550 nm obtained for all the structures of phenolic compounds studied, ortho-alkyl substituted yielded selectively a metastable band at 400 nm, due to gold nanoclusters (AuNCs) formation. We hypothesized that these specific phenolic compounds can temporally stabilize AuNCs with number of Au atoms ranging from 3 to 41. This new band was proposed for rapid screening of these phenolics with promising results, paving the way to new and more selective colorimetric assay for phenolic compounds determination.eninfo:eu-repo/semantics/openAccess23 QuímicaartículoPhenolic compoundsAntioxidantsGold nanoclusterGold nanoparticleIsomer analysis