Ordered mesoporous molecular sieves as active catalyts for the synthesis of 1,4-dihydropyridine derivatives

Calvino-Casilda, Vanesa y Martín-Aranda, Rosa . (2020) Ordered mesoporous molecular sieves as active catalyts for the synthesis of 1,4-dihydropyridine derivatives. Catalysis Today, Volume 354, 1 September 2020, Pages 44-50


Título Ordered mesoporous molecular sieves as active catalyts for the synthesis of 1,4-dihydropyridine derivatives
Autor(es) Calvino-Casilda, Vanesa
Martín-Aranda, Rosa
Materia(s) Química
Abstract Research on heterocyclic compounds with biological and pharmacological activity continues to arouse great interest. The study of 1,4-dihydropyridines (1,4-DHPs) is of particular interest in the pharmaceutical field due to their important applications as calcium channel antagonists for the treatment of heart diseases. The implementation of novel heterogeneous catalysts to optimize Hantzsch synthesis, such as ordered mesoporous molecular sieves, is an efficient and eco-friendly proposal that still requires a lot of work. The remarkable features of ordered mesoporous molecular sieves, such as high surface area, tailored porosity, chemical and thermal stability, among others, turn these materials into powerful solid catalysts capable of selectively leading the synthesis of 1,4-DHPs. In addition, the combination of ordered mesoporous molecular sieves and process intensification for the synthesis of 1,4-DHP derivatives is still a research field in development. Therefore, promote greener methodologies in the synthesis of 1,4-DHPs that can be extended to any organic synthesis in fine chemical production is an important goal yet to be achieved.
Palabras clave Ordered mesoporous molecular sieves
Heterogeneous catalysis
Heterocyclic scaffolds
1,4-Dihydropyridines
Editor(es) Elsevier
Fecha 2020-09-01
Formato application/pdf
Identificador bibliuned:DptoQIyQT-FCIE-Articulos-Rmmartin-0006
http://e-spacio.uned.es/fez/view/bibliuned:DptoQIyQT-FCIE-Articulos-Rmmartin-0006
DOI - identifier 10.1016/j.cattod.2019.06.046
ISSN - identifier 1873-4308
Nombre de la revista Catalysis Today
Número de Volumen 354
Página inicial 44
Página final 50
Publicado en la Revista Catalysis Today, Volume 354, 1 September 2020, Pages 44-50
Idioma eng
Versión de la publicación publishedVersion
Tipo de recurso Article
Derechos de acceso y licencia http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/closedAccess
Tipo de acceso Acceso cerrado
Notas adicionales The registered version of this article, first published in Catalysis Today, is available online at the publisher's website: Elsevier, https://doi.org/10.1016/j.cattod.2019.06.046

 
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Creado: Thu, 25 Jan 2024, 21:52:11 CET