Rheological Properties of Different Graphene Nanomaterials in Biological Media

Cerpa Naranjo, Arisbel, Pérez Piñeiro, Javier, Navajas Chocarro, Pablo, Lado Touriño, Isabel, Barrios Bermúdez, Niurka, Moreno, Rodrigo y Rojas-Cervantes, María Luisa . (2022) Rheological Properties of Different Graphene Nanomaterials in Biological Media. Nanomaterials

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Título Rheological Properties of Different Graphene Nanomaterials in Biological Media
Autor(es) Cerpa Naranjo, Arisbel
Pérez Piñeiro, Javier
Navajas Chocarro, Pablo
Lado Touriño, Isabel
Barrios Bermúdez, Niurka
Moreno, Rodrigo
Rojas-Cervantes, María Luisa
Materia(s) Química
Abstract Carbon nanomaterials have received increased attention in the last few years due to their potential applications in several areas. In medicine, for example, these nanomaterials could be used as contrast agents, drug transporters, and tissue regenerators or in gene therapy. This makes it necessary to know the behavior of carbon nanomaterials in biological media to assure good fluidity and the absence of deleterious effects on human health. In this work, the rheological characterization of different graphene nanomaterials in fetal bovine serum and other fluids, such as bovine serum albumin and water, is studied using rotational and microfluidic chip rheometry. Graphene oxide, graphene nanoplatelets, and expanded graphene oxide at concentrations between 1 and 3 mg/mL and temperatures in the 25–40 ◦C range were used. The suspensions were also characterized by transmission and scanning electron microscopy and atomic force microscopy, and the results show a high tendency to aggregation and reveals that there is a protein–nanomaterial interaction. Although rotational rheometry is customarily used, it cannot provide reliable measurements in low viscosity samples, showing an apparent shear thickening, whereas capillary viscometers need transparent samples; therefore, microfluidic technology appears to be a suitable method to measure low viscosity, non-transparent Newtonian fluids, as it is able to determine small variations in viscosity. No significant changes in viscosity are found within the solid concentration range studied but it decreases between 1.1 and 0.6 mPa·s when the temperature raises from 25 to 40 ◦C.
Palabras clave rheology
carbon-based nanomaterials
biological fluids
fetal bovine serum
bovine serum albumin
Editor(es) MDPI
Fecha 2022-05-18
Formato application/pdf
Identificador bibliuned:DptoQIyQT-FCIE-Articulos-Mlrojas-0003
http://e-spacio.uned.es/fez/view/bibliuned:DptoQIyQT-FCIE-Articulos-Mlrojas-0003
DOI - identifier https://doi.org/10.3390/ma15103593
ISSN - identifier 1996-1944
Nombre de la revista Materials
Número de Volumen 15
Número de Issue 10
Página inicial 3593-1
Página final 3593-15
Publicado en la Revista Nanomaterials
Idioma eng
Versión de la publicación publishedVersion
Tipo de recurso Article
Derechos de acceso y licencia http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
Tipo de acceso Acceso abierto
Notas adicionales La versión registrada de este artículo, publicada por primera vez en Materials (2022) 15, está disponible en línea en el sitio web de la editorial: MDPI, https://doi.org/10.3390/ma15103593
Notas adicionales The registered version of this article, first published in Materials (2022) 15, is available online at the publisher's website: MDPI, https://doi.org/10.3390/ma15103593

Tipo de documento: Artículo de revista
Collection: Departamento de Química Inorgánica y Química Técnica (UNED). Artículos
 
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Creado: Thu, 22 Feb 2024, 00:35:03 CET