Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial

Haro-Martínez, Ana M., Lubrini, Genny, Madero-Jarabo, Rosario, Díez-Tejedor, Exuperio y Fuentes, Blanca . (2018) Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial. Clinical Rehabilitation

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Título Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial
Autor(es) Haro-Martínez, Ana M.
Lubrini, Genny
Madero-Jarabo, Rosario
Díez-Tejedor, Exuperio
Fuentes, Blanca
Materia(s) Psicología
Abstract Objective: To collect data to estimate the sample size of a definitive randomized controlled trial to evaluate the effects of Melodic Intonation Therapy in post-stroke nonfluent aphasia. Design: A randomized, crossover, interventional pilot trial. Setting: Departments of Neurology and Rehabilitation from a university general hospital. Participants: Stroke survivors with post-stroke nonfluent aphasia. Interventions: Patients randomized to group 1 had treatment with Melodic Intonation Therapy first (12 sessions over six weeks) followed by no treatment; the patients in group 2 started active treatment between three and six months after their inclusion in the study, serving as waiting list controls for the first phase. Main measures: The Communicative Activity Log (CAL) questionnaire and the Boston Diagnostic Aphasia Examination (BDAE) were evaluated at baseline, and at six and 12 weeks. Results: Twenty patients were included. Four of the patients allocated to group 2 crossed over to group 1, receiving the treatment at first. Intention-to-treat analysis: after adjustment for baseline scores, the mean difference in the CAL evaluation from baseline in the treated group was 8.5 points (95% confidence interval (CI), 0.11–17.0; P = .043), with no significant change in any of the BDAE sections. Per-protocol analysis showed similar results with a clear treatment effect (P = .043) on the CAL. Conclusion: Melodic Intonation Therapy might have a positive effect on the communication skills of stroke survivors with nonfluent aphasia as measured by the CAL questionnaire. A full-scale trial with at least 27 patients per group is necessary to confirm these results.
Palabras clave ischaemic stroke
aphasia
melodic intonation therapy
Editor(es) SAGE
Fecha 2018-06-30
Formato application/pdf
Identificador bibliuned:DptoPBII-FPSI-Articulos-Glubrini-0004
http://e-spacio.uned.es/fez/view/bibliuned:DptoPBII-FPSI-Articulos-Glubrini-0004
DOI - identifier 10.1177/0269215518791004
ISSN - identifier 1477-0873
Nombre de la revista Clinical Rehabilitation
Número de Volumen 33
Página inicial 44
Página final 53
Publicado en la Revista Clinical Rehabilitation
Idioma eng
Versión de la publicación acceptedVersion
Tipo de recurso Article
Derechos de acceso y licencia http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
Tipo de acceso Acceso abierto
Notas adicionales The registered version of this article, first published in Clinical Rehabilitation, is available online at the publisher's website: SAGE https://doi.org/10.1177/0269215518791004
Notas adicionales La versión registrada de este artículo, publicado por primera vez en Clinical Rehabilitation, está disponible en línea en el sitio web del editor: SAGE https://doi.org/10.1177/0269215518791004

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Creado: Tue, 30 Jan 2024, 00:20:42 CET