Cognitive deficits and clinical symptoms in patients with treatment-refractory obsessive–compulsive disorder: The role of slowness in information processing

Simón-Martínez, Vanesa, Laseca-Zaballa, Garazi, Lubrini, Genny, Periáñez, José A., Martínez Álvarez, Roberto, Torres-Díaz, Cristina V., Martínez Moreno, Nuria, Alvarez-Linera, Juan y Ríos-Lago, Marcos . (2021) Cognitive deficits and clinical symptoms in patients with treatment-refractory obsessive–compulsive disorder: The role of slowness in information processing. Psychiatry Research

Ficheros (Some files may be inaccessible until you login with your e-spacio credentials)
Nombre Descripción Tipo MIME Size
Lubrini_Genny_Cognitive_deficits_and_clinical_symptoms.pdf Lubrini_Genny_Cognitive deficits and clinical symptoms.pdf application/pdf 2.46MB

Título Cognitive deficits and clinical symptoms in patients with treatment-refractory obsessive–compulsive disorder: The role of slowness in information processing
Autor(es) Simón-Martínez, Vanesa
Laseca-Zaballa, Garazi
Lubrini, Genny
Periáñez, José A.
Martínez Álvarez, Roberto
Torres-Díaz, Cristina V.
Martínez Moreno, Nuria
Alvarez-Linera, Juan
Ríos-Lago, Marcos
Materia(s) Psicología
Abstract Patients with Obsessive–Compulsive Disorder (OCD) present neuropsychological deficits across different cognitive domains, especially in executive functioning and information processing speed. Some studies have even suggested that speed deficits may underlie poor neuropsychological performance. However, this hypothesis remains unanswered in both OCD general population and OCD refractory subgroup. In addition, it is not clear whether such deficits are secondary to the clinical symptoms or may constitute a primary deficit. The aim of this study was to explore the speed of processing hypothesis in treatment-refractory OCD patients, and to clarify to what extent slowness is related to psychopathological symptoms. Both clinical and neuropsychological examination was conducted to assess 39 OCD refractory patients candidates for neurosurgery and 39 healthy matched individuals. Principal component analysis revealed a three-component structure in the neuropsychological battery being used, including a speed of processing, working memory, and conflict monitoring components. Group comparisons revealed that OCD patients performed significantly worse than healthy individuals in speed measures, but no differences were found in executive tests not influenced by time. Correlation analyses revealed a lack of association between neuropsychological and clinical measures. The results suggest that treatment-refractory OCD patients exhibit a primary deficit in information processing speed independent of clinical symptoms.
Palabras clave attention mechanism
Clinical symptoms
Executive function
Information processing speed
Neuropsychology
Obsessive–compulsive disorder
Slowness
Editor(es) Elsevier
Fecha 2021-10
Formato application/pdf
Identificador bibliuned:DptoPBII-FPSI-Articulos-Glubrini-0001
http://e-spacio.uned.es/fez/view/bibliuned:DptoPBII-FPSI-Articulos-Glubrini-0001
DOI - identifier 10.1016/j.psychres.2021.114143
ISSN - identifier 0165-1781
Nombre de la revista Psychiatry Research
Número de Volumen 304
Publicado en la Revista Psychiatry Research
Idioma eng
Versión de la publicación acceptedVersion
Tipo de recurso Article
Derechos de acceso y licencia http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
Tipo de acceso Acceso abierto
Notas adicionales The registered version of this article, first published in Psychiatry Research, is available online at the publisher's website: Elsevier https://doi.org/10.1016/j.psychres.2021.114143
Notas adicionales La versión registrada de este artículo, publicado por primera vez en Psychiatry Research, está disponible en línea en el sitio web del editor: Elsevier https://doi.org/10.1016/j.psychres.2021.114143

Tipo de documento: Artículo de revista
Collections: Departamento de Psicología Básica II. Artículos
Set de artículo
Set de openaire
 
Versiones
Versión Tipo de filtro
Contador de citas: Google Scholar Search Google Scholar
Estadísticas de acceso: 44 Visitas, 10 Descargas  -  Estadísticas en detalle
Creado: Mon, 29 Jan 2024, 23:57:32 CET