Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius

Fuente, Mercedes de la, Martín Folgar, Raquel, Martínez Paz, Pedro, Cortés, Pedro, Martínez Guitarte José Luis y Morales, Mónica . (2022) Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius. Environmental Science and Pollution Research, Volume 29, pages 10210–10221

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Título Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius
Autor(es) Fuente, Mercedes de la
Martín Folgar, Raquel
Martínez Paz, Pedro
Cortés, Pedro
Martínez Guitarte José Luis
Morales, Mónica
Materia(s) Ciencias
Abstract Chemical compounds produced by humans are continuously reaching the environment. In this work, we characterised the expression patterns of important endocrine-related genes involved in the ecdysone pathway in the fourth larval instar of the model species Chironomus riparius after exposure to three chemicals: ethinyl oestradiol (EE), nonylphenol (NP) and bis(tributyltin) oxide (TBTO). We used real-time PCR to analyse the gene expression levels of ecdysone receptor (EcR) and ultraspiracle (usp), two genes that encode the dimerising partners of the functional ecdysone receptor; the orphan receptor ERR (oestrogen-related receptor), with an unknown function in invertebrates; and E74, an early response gene induced by ecdysteroids. We estimated the bioaccumulation potential, bioavailability and physicochemical properties of these chemicals, together with a number of other exogenous agents known to interfere with the hormonal system. We also provide a review of previous transcriptional studies showing the effect of all these chemicals on ecdysone cascade genes. This analysis provides useful data for future ecotoxicological studies involving invertebrate species
Palabras clave Endocrine-disrupting chemicals (EDCs)
Chironomus riparius
Toxicity
Transcriptional response
Editor(es) Springer
Fecha 2022-02
Formato application/pdf
Identificador bibliuned:DptoFMyF-FCIE-Articulos-Mmorales-0004
http://e-spacio.uned.es/fez/view/bibliuned:DptoFMyF-FCIE-Articulos-Mmorales-0004
DOI - identifier https://doi.org/10.1007/s11356-021-16339-3
ISSN - identifier 0944-1344; eISSN: 1614-7499
Nombre de la revista Environmental Science and Pollution Research
Número de Volumen 29
Página inicial 10210
Página final 10221
Publicado en la Revista Environmental Science and Pollution Research, Volume 29, pages 10210–10221
Idioma eng
Versión de la publicación publishedVersion
Tipo de recurso Article
Derechos de acceso y licencia http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
Tipo de acceso Acceso abierto
Notas adicionales The registered version of this article, first published in "Environmental Science and Pollution Research, Volume 29, pages 10210–10221", is available online at the publisher's website: Springer, https://doi.org/10.1007/s11356-021-16339-3
Notas adicionales La versión registrada de este artículo, publicado por primera vez en "Environmental Science and Pollution Research, Volume 29, pages 10210–10221, está disponible en línea en el sitio web del editor: Springer, https://doi.org/10.1007/s11356-021-16339-3

 
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Creado: Wed, 24 Jan 2024, 21:16:11 CET