Fast detection of the main anatomical structures in digital retinal images based on intra-and inter-structure relational knowledge

Molina Casado, José M., Carmona, Enrique J. y García Feijoó, Julián . (2017) Fast detection of the main anatomical structures in digital retinal images based on intra-and inter-structure relational knowledge. Computer Methods and Programs in Biomedicine Vol.149, 55–68 (2017)

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Título Fast detection of the main anatomical structures in digital retinal images based on intra-and inter-structure relational knowledge
Autor(es) Molina Casado, José M.
Carmona, Enrique J.
García Feijoó, Julián
Materia(s) Informática
Ingeniería Informática
Abstract Background and objective: The anatomical structure detection in retinal images is an open problem. However, most of the works in the related literature are oriented to the detection of each structure individually or assume the previous detection of a structure which is used as a reference. The objective of this paper is to obtain simultaneous detection of the main retinal structures (optic disc, macula, network of vessels and vascular bundle) in a fast and robust way. Methods: We propose a new methodology oriented to accomplish the mentioned objective. It consists of two stages. In an initial stage, a set of operators is applied to the retinal image. Each operator uses intra-structure relational knowledge in order to produce a set of candidate blobs that belongs to the desired structure. In a second stage, a set of tuples is created, each of which contains a different combination of the candidate blobs. Next, filtering operators, using inter-structure relational knowledge, are used in order to find the winner tuple. A method using template matching and mathematical morphology is implemented following the proposed methodology. Results: A success is achieved if the distance between the automatically detected blob center and the actual structure center is less than or equal to one optic disc radius. The success rates obtained in the different public databases analyzed were: MESSIDOR (99.33%, 98.58%, 97.92%), DIARETDB1 (96.63%, 100%, 97.75%), DRIONS (100%, n/a, 100%) and ONHSD (100%, 98.85%, 97.70%) for optic disc (OD), macula (M) and vascular bundle (VB), respectively. Finally, the overall success rate obtained in this study for each structure was: 99.26% (OD), 98.69% (M) and 98.95% (VB). The average time of processing per image was 4.16 ± 0.72 s. Conclusions: The main advantage of the use of inter-structure relational knowledge was the reduction of the number of false positives in the detection process. The implemented method is able to simultaneously detect four structures. It is fast, robust and its detection results are competitive in relation to other methods of the recent literature.
Palabras clave Retinal image
Anatomical structure detection
Optic disc
Macula
Vessel network
Vascular bundle
Editor(es) Elsevier
Fecha 2017-10
Formato application/pdf
Identificador bibliuned:95-Ejcarmona-0008
http://e-spacio.uned.es/fez/view/bibliuned:95-Ejcarmona-0008
DOI - identifier http://dx.doi.org/10.1016/j.cmpb.2017.06.022
ISSN - identifier 1872-7565
Nombre de la revista Computer Methods and Programs in Biomedicine
Número de Volumen 149
Página inicial 55
Página final 68
Publicado en la Revista Computer Methods and Programs in Biomedicine Vol.149, 55–68 (2017)
Idioma eng
Versión de la publicación acceptedVersion
Tipo de recurso Article
Derechos de acceso y licencia http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/embargoedAccess
Tipo de acceso Acceso abierto
Notas adicionales This is an Accepted Manuscript of an article published by Elsevier in "Computer Methods and Programs in Biomedicine Vol.149, 55–68 (2017)", available at: http://dx.doi.org/10.1016/j.cmpb.2017.06.022
Notas adicionales Este es el manuscrito aceptado del artículo publicado por Elsevier en "Computer Methods and Programs in Biomedicine Vol.149, 55–68 (2017)", disponible en línea: http://dx.doi.org/10.1016/j.cmpb.2017.06.022

 
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